How Much Is Artesunate In Nigeria?
What are the effects of artesunate?
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– Hives.
– Rash.
– Hemoglobinuria.
– Seizures.
– Neuropsychiatric reactions.
– Reversible neurologic changes.
Is artesunate a prescription drug?
Artesunate is used to treat severe malaria. Artesunate is not FDA approved nor commercially available in the U.S.; however, the Centers for Disease Control (CDC) has taken action to ensure intravenous (IV) artesunate is available through an expanded use investigational new drug (IND) protocol.
What is the other name for artesunate?
Artesunate/amodiaquine, sold under the trade name Camoquin among others, is a medication used for the treatment of malaria.
How do I order artesunate?
– Hospital pharmacist should contact their drug distributor to request an EMERGENCY procurement of Artesunate for Injection. …
– If your hospital distributor is unable to provide artesunate then call Cardinal Specialty Pharmacy to request artesunate.
What is the generic name for artesunate?
Artesunate is a white or almost white powder with a molecular weight of 384.43. The chemical name is butanedioic acid, mono[(3R,5aS,6R,8aS,9R,10S,12R,12aR)-decahydro-3,6,9-trimethyl-3,12-epoxy-12Hpyrano[4,3-j]-1,2-benzodioxepin-10-yl] ester. The empirical formula is C19H28O8.
What is artesunate Injection used for?
Artesunate injection is used to treat severe malaria. This medicine is also used together with other medicines (eg, 8-aminoquinoline medicine) to treat severe malaria caused by Plasmodium ovale or Plasmodium vivax. Artesunate belongs to a group of medicines known as antimalarials.
Is artesunate licensed in UK?
However, there is no parenteral formulation of artesunate made to Good Manufacturing Practice standards, so it is not licensed in the UK and has not been endorsed as first-line treatment in national guidelines.
What class of drug is artesunate?
Artesunate was developed by Liu Xu in 1977. It is on the World Health Organization’s List of Essential Medicines. It was approved for medical use in the United States in May 2020. It is in the class of medications known as artemisinins, which are derivatives from qinghao or sweet wormwood plant (Artemisia annua).
Is artemisinin a prescription drug?
Artemisinins have been available in the United States without a prescription as herbal supplements for at least 10 years; these supplements are marketed for general health maintenance and for treatment of parasitic infections and cancers.A
How does artesunate work in the body?
Artesunate is an artemisinin derivative that is metabolized to DHA, which generates free radicals to inhibit normal function of Plasmodium parasites. It has a short duration of action due to its short half life, and a moderate therapeutic index.O
Is artesunate an antibiotic?
By compromising NO-mediated protection from antibiotics and triggering harmful hydrogen peroxide burst, artesunate may serve as a promising antibiotic synergist for killing the multidrug resistant pathogenic bacteria.J
How much does malaria drugs cost in Nigeria?
Average amount charged patient for treating uncomplicated malaria in private hospitals was N3,941. Average amount spent on antimalarial drugs was about N2,443 (62%) while N1,064 (27.7%) was spent on laboratory investigation and N406.
How much does artesunate cost?
Yet that approval was accompanied by a 150-fold jump in price: Artesunate costs about $30,000 for an average course of treatment for an adult, compared to less than $200 for quinidine in 2018.J
Is artemisinin approved by FDA?
Today, Coartem is produced by Novartis in China and the United States and is the most widely used artemisinin combination worldwide. Food and Drug Administration (FDA) approval was given for use of artemether-lumefantrine in the United States in April 2009.
What is the mode of action for artesunate?
Artesunate is an artemisinin derivative that is metabolized to DHA, which generates free radicals to inhibit normal function of Plasmodium parasites. It has a short duration of action due to its short half life, and a moderate therapeutic index.O
